ABOLISHED KETAMINE EFFECTS ON THE SPONTANEOUS EXCITATORY POSTSYNAPTIC CURRENT OF MEDIAL PREFRONTAL CORTEX NEURONS IN GLUN2D KNOCKOUT MICE

Abolished ketamine effects on the spontaneous excitatory postsynaptic current of medial prefrontal cortex neurons in GluN2D knockout mice

Abstract Ketamine, a non-competitive antagonist of the N-methyl-d-aspartate receptor (NMDAR), generates a rapidly-acting antidepressant effect.It exerts psychomimetic effects, yet demands a further investigation of its mechanism.Previous research showed that ketamine did no longer promote hyperlocomotion in GluN2D knockout (KO) mice, Dining Chair S

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Delayed Presentation of Congenital Diaphragmatic Hernia with Acute Respiratory Distress: Challenges in Diagnosis and Management

Delayed presentation of congenital diaphragmatic hernia (CDH) with acute respiratory distress beyond the newborn period may poise challenges in diagnosis and management.We report a 3-month-old infant who presented with acute-onset respiratory distress and left congenital diaphragmatic hernia that was relieved with Coffee Table thoracoscopic repair.

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